Ryan P. McGlinchey : rechercher sur Z-Library

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1

The Fluorinase from Streptomyces cattleya Is Also a Chlorinase

Hai Deng, Steven L. Cobb, Andrew R. McEwan, Ryan P. McGlinchey, James H. Naismith, David O'Hagan, David A. Robinson, Jonathan B. Spencer

Journal:

Angewandte Chemie

Année:

2006

Langue:

english

Fichier:

PDF, 189 KB

english, 2006

2

In Vitro Reconstituted Biotransformation of 4-Fluorothreonine from Fluoride Ion: Application of the Fluorinase

Hai Deng, Stuart M. Cross, Ryan P. McGlinchey, John T.G. Hamilton, David O'Hagan

Journal:

Chemistry & Biology

Année:

2008

Langue:

english

Fichier:

PDF, 697 KB

english, 2008

3

Insights into fluorometabolite biosynthesis in Streptomyces cattleya DSM46488 through genome sequence and knockout mutants

Chunhua Zhao, Peng Li, Zixin Deng, Hong-Yu Ou, Ryan P. McGlinchey, David O’Hagan

Journal:

Bioorganic Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 628 KB

english, 2012

4

Identification of 5-Fluoro-5-deoxy-D-ribose-1-phosphate as an Intermediate in Fluorometabolite Biosynthesis in Streptomyces cattleya.

Steven L. Cobb, Hai Deng, John T. G. Hamilton, Ryan P. McGlinchey, David O'Hagan

Journal:

Année:

2004

Fichier:

PDF, 53 KB

2004

5

Identification of 5-fluoro-5-deoxy-d-ribose-1-phosphate as an intermediate in fluorometabolite biosynthesis in Streptomyces cattleya

Cobb, Steven L., Deng, Hai, Hamilton, John T. G., McGlinchey, Ryan P., O'Hagan, David

Journal:

Chemical Communications

Année:

2004

Langue:

english

Fichier:

PDF, 165 KB

english, 2004

6

The Fluorinase from Streptomyces cattleya Is Also a Chlorinase

Hai Deng, Steven L. Cobb, Andrew R. McEwan, Ryan P. McGlinchey, James H. Naismith, David O'Hagan, David A. Robinson, Jonathan B. Spencer

Journal:

Angewandte Chemie International Edition

Année:

2006

Langue:

english

Fichier:

PDF, 189 KB

english, 2006

7

The identification of 5′-fluoro-5-deoxyinosine as a shunt product in cell free extracts of Streptomyces cattleya

Steven L. Cobb, Hai Deng, John T.G. Hamilton, Ryan P. McGlinchey, David O’Hagan, Christoph Schaffrath

Journal:

Bioorganic Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 209 KB

english, 2005

8

The identification of (3R,4S)-5-fluoro-5-deoxy-d-ribulose-1-phosphate as an intermediate in fluorometabolite biosynthesis in Streptomyces cattleya

Mayca Onega, Ryan P. McGlinchey, Hai Deng, John T.G. Hamilton, David O’Hagan

Journal:

Bioorganic Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 434 KB

english, 2007

9

Advances in and applications of proteasome inhibitors

Bradley S Moore, Alessandra S Eustáquio, Ryan P McGlinchey

Journal:

Current Opinion in Chemical Biology

Année:

2008

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2008

10

Prion amyloid structure explains templating: how proteins can be genes

Reed B. Wickner, Frank Shewmaker, Herman Edskes, Dmitry Kryndushkin, Julie Nemecek, Ryan McGlinchey, David Bateman, Chia-Lin Winchester

Journal:

FEMS Yeast Research

Année:

2010

Langue:

english

Fichier:

PDF, 526 KB

english, 2010

11

Genomic islands link secondary metabolism to functional adaptation in marine Actinobacteria

Penn, Kevin, Jenkins, Caroline, Nett, Markus, Udwary, Daniel W, Gontang, Erin A, McGlinchey, Ryan P, Foster, Brian, Lapidus, Alla, Podell, Sheila, Allen, Eric E

Journal:

The ISME Journal

Année:

2009

Langue:

english

Fichier:

PDF, 883 KB

english, 2009

12

The relationship of prions and translation

Reed B. Wickner, Herman K. Edskes, Frank P. Shewmaker, Dmitry Kryndushkin, Julie Nemecek, Ryan McGlinchey, David Bateman

Journal:

Wiley Interdisciplinary Reviews: RNA

Année:

2010

Langue:

english

Fichier:

PDF, 296 KB

english, 2010

13

Bacterial Self-Resistance to the Natural Proteasome Inhibitor Salinosporamide A

Kale, Andrew J., McGlinchey, Ryan P., Lechner, Anna, Moore, Bradley S.

Journal:

ACS Chemical Biology

Année:

2011

Langue:

english

Fichier:

PDF, 859 KB

english, 2011

14

CFD investigation of dense phase pneumatic conveying at a pipeline enlargement

Don McGlinchey, Andrew Cowell, Ryan Crowe

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.47 MB

english, 2012

15

Prion diseases of yeast: Amyloid structure and biology

Reed B. Wickner, Herman K. Edskes, Dmitry Kryndushkin, Ryan McGlinchey, David Bateman, Amy Kelly

Journal:

Seminars in Cell & Developmental Biology

Année:

2011

Langue:

english

Fichier:

PDF, 744 KB

english, 2011

16

Segmental Polymorphism in a Functional Amyloid

Hu, Kan-Nian, McGlinchey, Ryan P., Wickner, Reed B., Tycko, Robert

Journal:

Biophysical Journal

Année:

2011

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2011

17

The Repeat Domain of Pmel17 Orthologs Form Amyloid Fibrils at the Acidic Melanosomal pH

McGlinchey, Ryan P., Pfefferkorn, Candace M., Wickner, Reed B., Lee, Jennifer C.

Journal:

Biophysical Journal

Année:

2011

Langue:

english

Fichier:

PDF, 41 KB

english, 2011

18

REPORT OF THE LANCET

Jiang, Zhiping, McGlinchey, Ryan P., Pfefferkorn, Candace M., Lee, Jennifer C.

Journal:

Année:

1888

Langue:

english

Fichier:

PDF, 390 KB

english, 1888

19

Effects of Lipids on the Conformation and Aggregation of the Repeat Domain of a Functional Amyloid, Pmel17

Jiang, Zhiping, McGlinchey, Ryan P., Pfefferkorn, Candace M., Lee, Jennifer C.

Journal:

Biophysical Journal

Année:

2012

Langue:

english

Fichier:

PDF, 38 KB

english, 2012

20

Effects of Molecular Crowding on the Repeat Domain of a Functional Amyloid, Pmel17

McGlinchey, Ryan P., Jiang, Zhiping, Lee, Jennifer C.

Journal:

Biophysical Journal

Année:

2013

Langue:

english

Fichier:

PDF, 39 KB

english, 2013

21

Mimicking Lysosomal Degradation of α-Synuclein

Lee, Jennifer C., McGlinchey, Ryan P., Vargas, Mercedes

Journal:

Biophysical Journal

Année:

2014

Langue:

english

Fichier:

PDF, 40 KB

english, 2014

22

Molecular Details of α-Synuclein Membrane Association Revealed by Neutron Reflectometry

Lee, Jennifer C., Jiang, Zhiping, Hess, Sara, McGlinchey, Ryan P., Leong Yap, Thai, Heinrich, Frank

Journal:

Biophysical Journal

Année:

2014

Langue:

english

Fichier:

PDF, 43 KB

english, 2014

23

Unraveling the Biosynthesis of the Sporolide Cyclohexenone Building Block

McGlinchey, Ryan P., Nett, Markus, Moore, Bradley S.

Journal:

Journal of the American Chemical Society

Année:

2008

Langue:

english

Fichier:

PDF, 91 KB

english, 2008

24

Probing Fibril Dissolution of the Repeat Domain of a Functional Amyloid, Pmel17, on the Microscopic and Residue Level

McGlinchey, Ryan P., Gruschus, James M., Nagy, Attila, Lee, Jennifer C.

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 909 KB

english, 2011

25

Engineered Biosynthesis of Antiprotealide and Other Unnatural Salinosporamide Proteasome Inhibitors

McGlinchey, Ryan P., Nett, Markus, Eustáquio, Alessandra S., Asolkar, Ratnakar N., Fenical, William, Moore, Bradley S.

Journal:

Journal of the American Chemical Society

Année:

2008

Langue:

english

Fichier:

PDF, 371 KB

english, 2008

26

The yin and yang of amyloid: insights from α-synuclein and repeat domain of Pmel17

McGlinchey, Ryan P., Yap, Thai Leong, Lee, Jennifer C.

Journal:

Physical Chemistry Chemical Physics

Année:

2011

Langue:

english

Fichier:

PDF, 2.18 MB

english, 2011

27

Fluorinase mediated C–18F bond formation, an enzymatic tool for PET labelling

Deng, Hai, Cobb, Steven L., Gee, Antony D., Lockhart, Andrew, Martarello, Laurent, McGlinchey, Ryan P., O'Hagan, David, Onega, Mayca

Journal:

Chemical Communications

Année:

2006

Langue:

english

Fichier:

PDF, 291 KB

english, 2006

28

Cover Picture: Molecular Origin of pH-Dependent Fibril Formation of a Functional Amyloid (ChemBioChem 11/2014)

McGlinchey, Ryan P., Jiang, Zhiping, Lee, Jennifer C.

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 703 KB

english, 2014

29

Molecular Origin of pH-Dependent Fibril Formation of a Functional Amyloid

McGlinchey, Ryan P., Jiang, Zhiping, Lee, Jennifer C.

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2014

30

Cysteine cathepsins are essential in lysosomal degradation of α-synuclein

McGlinchey, Ryan P., Lee, Jennifer C.

Journal:

Proceedings of the National Academy of Sciences

Année:

2015

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2015

31

Suicidal [PSI⁺] is a lethal yeast prion

Ryan P. McGlinchey, Dmitry Kryndushkin and Reed B. Wickner

Journal:

Proceedings of the National Academy of Sciences

Année:

2011

Langue:

english

Fichier:

PDF, 1.27 MB

english, 2011

32

Effects of pH on aggregation kinetics of the repeat domain of a functional amyloid, Pmel17

Candace M. Pfefferkorn, Ryan P. McGlinchey, Jennifer C. Lee and Harry B. Gray

Journal:

Proceedings of the National Academy of Sciences

Année:

2010

Langue:

english

Fichier:

PDF, 1.37 MB

english, 2010

33

Segmental Deuteration of α-Synuclein for Neutron Reflectometry on Tethered Bilayers

Jiang, Zhiping, Heinrich, Frank, McGlinchey, Ryan P., Gruschus, James M., Lee, Jennifer C.

Journal:

The Journal of Physical Chemistry Letters

Année:

2017

Langue:

english

Fichier:

PDF, 1.75 MB

english, 2017

34

Reversing the Amyloid Trend: Mechanism of Fibril Assembly and Dissolution of the Repeat Domain from a Human Functional Amyloid

McGlinchey, Ryan P., Lee, Jennifer C.

Journal:

Israel Journal of Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 3.55 MB

english, 2017

35

Antibody-drug conjugates bearing pyrrolobenzodiazepine or tubulysin payloads are immunomodulatory and synergize with multiple immunotherapies

Rios-Doria, Jonathan, Harper, Jay, Rothstein, Raymond, Wetzel, Leslie, Chesebrough, Jon, Marrero, Allison M, Chen, Cui, Strout, Patrick, Mulgrew, Kathy, McGlinchey, Kelly A, Fleming, Ryan, Bezabeh, Bi

Journal:

Cancer Research

Année:

2017

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2017

36

Taking a Bite Out of Amyloid: Mechanistic Insights into α-Synuclein Degradation by Cathepsin L

McGlinchey, Ryan P., Dominah, Gifty, Lee, Jennifer C.

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 741 KB

english, 2017

37

Structural features of α-synuclein amyloid fibrils revealed by Raman spectroscopy

Flynn, Jessica D., McGlinchey, Ryan P., Walker, Robert L., Lee, Jennifer C.

Journal:

Journal of Biological Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2017

38

Why Study Functional Amyloids? Lessons from the Repeat Domain of Pmel17

McGlinchey, Ryan P., Lee, Jennifer C.

Journal:

Journal of Molecular Biology

Année:

2018

Langue:

english

Fichier:

PDF, 7.82 MB

english, 2018

39

Comprehensive analysis of the predictors of neurobehavioral symptom reporting in veterans

Andrews, Ryan J., Fonda, Jennifer R., Levin, Laura K., McGlinchey, Regina E., Milberg, William P.

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 328 KB

english, 2018

40

C-terminal α-synuclein truncations are linked to cysteine cathepsin activity in Parkinson’s disease

McGlinchey, Ryan P., Lacy, Shannon M., Huffer, Katherine E., Tayebi, Nahid, Sidransky, Ellen, Lee, Jennifer C.

Journal:

Journal of Biological Chemistry

Année:

2019

Langue:

english

Fichier:

PDF, 941 KB

english, 2019

41

Structural Insights into α-Synuclein Fibril Polymorphism: Effects of Parkinson's Disease-Related C-Terminal Truncations

Ni, Xiaodan, McGlinchey, Ryan P., Jiang, Jiansen, Lee, Jennifer C.

Journal:

Journal of Molecular Biology

Année:

2019

Langue:

english

Fichier:

PDF, 2.55 MB

english, 2019

42

Cardiorespiratory Fitness Is Associated With Better Cardiometabolic Health and Lower PTSD Severity in Post-9/11 Veterans

Whitworth, James W, Hayes, Scott M, Andrews, Ryan J, Fonda, Jennifer R, Beck, Brigitta M, Hanlon, Lilly B, Fortier, Catherine B, Milberg, William P, McGlinchey, Regina E

Journal:

Military Medicine

Année:

2020

Langue:

english

Fichier:

PDF, 182 KB

english, 2020

43

Cathepsin K is a potent disaggregase of Î±-synuclein fibrils

McGlinchey, Ryan P., Lacy, Shannon M., Walker, Robert L., Lee, Jennifer C.

Journal:

Biochemical and Biophysical Research Communications

Année:

2020

Fichier:

PDF, 1.51 MB

2020